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Lonza’s CHOK1SV and the GS System™
CHOK1SV was developed by Lonza to facilitate the creation of recombinant CHO cell lines for the production of biotherapeutics and to complement the power of the GS Expression vectors forming a complete expression system.
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| Productivity in chemically defined, animal component-free GS-CHO bioreactor process. The majority of our customers using the GS System™ will achieve more than 2g/L yield at GMP scale. |
Key Features
— Adapted to grow in chemically defined, animal component-free (CDACF) media
— Adapted to grow in single-cell suspension culture
— Exhibit good growth characteristics
* Reach high maximum viable cell concentrations
* Able to maintain cultures at high viability
— Capable of high productivity
— Easy scalability
— Established processes developed and widely used throughout the industry
These features enable highly productive and stable recombinant cell lines to be rapidly created and moved through to cGMP scale production in a seamless manner. Furthermore, the wide use of the GS System™ throughout the industry makes it familiar to and accepted by the regulatory authorities.
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