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Advantages of Potelligent® CHOK1SV
— The Potelligent® CHOK1SV cell line retains the desirable features of a high-productivity cell line (robust, high-yielding, scalable)
— Proven bioprocess platform for CHOK1SV is repeatable in the new cell line
— Antibodies produced by the new cell line:
* Can exert potent cytotoxic effects even when their target antigen density is low
* Retain all the other desirable features of antibodies such as Protein A binding
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The fucose-free antibodies produced by Potelligent® CHOK1SV show enhanced ADCC level compared to parental CHOK1SV cell line. Potelligent® CHOK1SV is already in use
with Lonza customers for development of therapeutic antibodies. The high productivity and enhanced antibody potency are expected to contribute to a signifi cant reduction
in the cost of goods for an antibody-based drug. |
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